I have done my PhD, thesis entitled “Search for novel phytochemicals against Leishmania donovani infection” under the supervision of Prof. Narayan Ghorai on 19.03.2019. My work dealt with the anti-proliferative effects of semi purified extracts of plants traditionally used by tribal healers and local people of Malda district, West Bengal, India, on both drug sensitive and drug resistant Leishmania donovani parasites. My sleuth lead me to identify semi purified fractions of three plants Argemone Mexicana, Murraya koenigii and Cinnamomum tamala to be highly active against miltefosine resistant Leishmania donovani promastigotes. I have also identified a semi purified fraction from an edible mushroom, Grifola frondosa, to be highly active against drug sensitive Leishmania donovani parasites. I have published my works in Experimental Parasitology (2014, 2018), Steroids (2016), Antimicrobial Agents and Chemotherapy (2016) and Infection and Immunity (2020).
My work have exposed me to animal cell culture, animal handling (Swiss Albino and BALB/c), Flow cytometry (analysis & experimental design), real time PCR, ELISA, enzyme kinetics assay, fluorescence microscopy (confocal), histology (H and E), HPLC (analysis), SEM (sample preparation) etc.